Article
Bisphenol a induces both transient and permanent histofunctional alterations of the hypothalamic-pituitary-gonadal axis in prenatally exposed male rats.
Endocrinology - 1 Jul 2003
Ramos Jorge G, Varayoud Jorgelina, Kass Laura, Rodríguez Horacio, Costabel Luciana, Muñoz-De-Toro Mónica, Luque Enrique H
Abstract excerpt
Exposure to bisphenol A (BPA) in utero has been shown to induce alterations in the prostate of 30-d-old Wistar rats. Herein, we examine both the time course of BPA action on the rat prostate and the effects of BPA on the male hypothalamic-pituitary-gonadal axis. This was achieved by exposing rats to BPA in utero, followed by immunohistochemistry and morphometric analysis of prostatic tissue, evaluation of...
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