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Article

Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2003

Singer Jason M, Shaw Janet M

Abstract excerpt

The evolutionarily conserved Mdm20 protein (Mdm20p) plays an important role in tropomyosin-F-actin interactions that generate actin filaments and cables in budding yeast. However, Mdm20p is not a structural component of actin filaments or cables, and its exact function in cable stability has remained a mystery. Here, we show that cells lacking Mdm20p fail to N-terminally acetylate Tpm1p, an abundant form of...

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Identifiers

PMID: 12808144
DOI: 10.1073/pnas.1232343100
PMCID: PMC164640

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.PMID 12808144Read ↗

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