Article
Canine X-linked muscular dystrophy in Japan (CXMDJ).
Experimental animals - 1 Apr 2003
Shimatsu Yoshiki, Katagiri Kouichi, Furuta Toshio, Nakura Masao, Tanioka Yoshikuni, Yuasa Katsutoshi, Tomohiro Masayuki, Kornegay Joe N, Nonaka Ikuya, Takeda Shin'ichi
Abstract excerpt
The purpose of this study was to develop a strain of canine X-linked muscular dystrophy (CXMD), a model of Duchenne muscular dystrophy, in Japan. A female beagle was artificially inseminated with frozen-thawed spermatozoa derived from an affected golden retriever. Subsequently, two carrier female dogs (G1 carriers) and four normal male littermates were produced. Thereafter, the two G1 carriers were mated with...
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