Article
Muscular dystrophy in a family of Labrador Retrievers with no muscle dystrophin and a mild phenotype.
Neuromuscular disorders : NMD - 1 May 2015
Vieira Natassia M, Guo Ling T, Estrela Elicia, Kunkel Louis M, Zatz Mayana, Shelton G Diane
Abstract excerpt
Animal models of dystrophin deficient muscular dystrophy, most notably canine X-linked muscular dystrophy, play an important role in developing new therapies for human Duchenne muscular dystrophy. Although the canine disease is a model of the human disease, the variable severity of clinical presentations in the canine may be problematic for pre-clinical trials, but also informative. Here we describe a family of...
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