Article
Identification of three distinguishable phenotypes in golden retriever muscular dystrophy.
Genetics and molecular research : GMR - 7 Apr 2009
Ambrósio C E, Fadel L, Gaiad T P, Martins D S, Araújo K P C, Zucconi E, Brolio M P, Giglio R F, Morini A C, Jazedje T, Froes T R, Feitosa M L T, Valadares M C, Beltrão-Braga P C B, Meirelles F V, Miglino M A
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a human disease characterized by progressive and irreversible skeletal muscle degeneration caused by mutations in genes coding for important muscle proteins. Unfortunately, there is no efficient treatment for this disease; it causes progressive loss of motor and muscular ability until death. The canine model (golden retriever muscular dystrophy) is similar to DMD, showing...
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