Article
Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells.
Biochemical and biophysical research communications - 27 Jun 2003
Taketomi Yoshitaka, Sugiki Toshihiko, Saito Takanori, Ishii Shin ichi, Hisada Masato, Suzuki-Nishimura Tamiko, Uchida Masaatsu K, Moon Tae Chul, Chang Hyeun Wook, Natori Yasuhiro, Miyazawa Shinobu, Kikuchi-Yanoshita Rei, Murakami Makoto, Kudo Ichiro
Abstract excerpt
Coculture of mouse bone marrow-derived mast cells (BMMC) with fibroblasts in the presence of stem cell factor (SCF) facilitates morphological and functional maturation toward a connective tissue mast cell (CTMC)-like phenotype. By means of cDNA subtraction, we identified several inducible genes during this mast cell maturation process. Of approximately 100 sequenced clones induced, nearly 50% were chromosome...
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