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Article

Cloning of TRAP, a ligand for CD40 on human T cells

1 Dec 1992

Abstract excerpt

A cDNA clone, designated TRAP (TNF-related activation protein) was isolated from a collection of T cell activation genes. The polypeptide encoded by a mRNA of approx. 2.3 kb is 261 amino acids long with a calculated M(r) of 29.3 kDa. The structural features predict a type II transmembrane protein, but are also compatible with a secreted form. TRAP is highly similar to an identified murine CD40 ligand both at the...

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PMID: 1280226
DOI: 10.1002/eji.1830221226

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