Article
Timing of paternal Pgk-1 expression in embryos of transgenic mice.
Development (Cambridge, England) - 1 Apr 1991
Pravtcheva D D, Adra C N, Ruddle F H
Abstract excerpt
In mouse development, the paternal allele of the X-linked gene Pgk-1 initiates expression on day 6, two days later than the maternal allele, which is activated on day 4. The different timing of expression of the maternal and paternal alleles may be determined by (i) imprinting of the chromosome region in which the gene resides, but not aimed specifically at the Pgk-1 gene; (ii) gene specific imprinting, acting on...
Topics
- Animals
- Cell Differentiation
- Embryo, Mammalian
- Gene Expression Regulation
- Genotype
- Mice
- Mice, Transgenic
- X Chromosome