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Article

Mouse endogenous X-linked genes do not show lineage-specific delayed inactivation during development.

Genetical research - 1 Jun 1995

Lebon J M, Tam P P, Singer-Sam J, Riggs A D, Tan S S

Abstract excerpt

X chromosome inactivation (XCI) has been assumed to be complete in all cells of female mouse embryos at about 6 d post coitum (dpc). However, a recent study on beta-galactosidase expression of an X-linked lacZ transgene suggests that XCI is probably not complete several days after this time in some lineages. To help resolve this issue, we analysed XCI in embryos which carry the T(X;16)16H (Searle's) translocation...

Topics

Alleles
Animals
Base Sequence
Dosage Compensation, Genetic
Female
Gene Expression Regulation, Developmental
Hypoxanthine Phosphoribosyltransferase
Mice
Molecular Sequence Data
Phosphoglycerate Kinase
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Translocation, Genetic

Source

Identifiers

PMID: 7615259
DOI: 10.1017/s0016672300033292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7615259-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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