Article
Mouse endogenous X-linked genes do not show lineage-specific delayed inactivation during development.
Genetical research - 1 Jun 1995
Lebon J M, Tam P P, Singer-Sam J, Riggs A D, Tan S S
Abstract excerpt
X chromosome inactivation (XCI) has been assumed to be complete in all cells of female mouse embryos at about 6 d post coitum (dpc). However, a recent study on beta-galactosidase expression of an X-linked lacZ transgene suggests that XCI is probably not complete several days after this time in some lineages. To help resolve this issue, we analysed XCI in embryos which carry the T(X;16)16H (Searle's) translocation...
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