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Article

Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.

Circulation - 17 Jun 2003

Gurbel Paul A, Bliden Kevin P, Hiatt Bonnie L, O'Connor Christopher M

Abstract excerpt

BACKGROUND: Clopidogrel is administered to prevent stent thrombosis; however, the uniformity of platelet inhibition after treatment and the influence of pretreatment reactivity on drug response have not been described. METHODS AND RESULTS: Platelet aggregation (5 and 20 micromol/L ADP), the activation of glycoprotein IIb/IIIa (PAC-1 antibody), and the expression of P-selectin were measured in patients undergoing...

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Source

Identifiers

PMID: 12796140
DOI: 10.1161/01.CIR.0000072771.11429.83

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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