Mechanisms of monozygotic (MZ) twinning: a possible role for the cell adhesion molecule, E-cadherin.

doi:10.1002/ajmg.a.20076

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Article

Mechanisms of monozygotic (MZ) twinning: a possible role for the cell adhesion molecule, E-cadherin.

American journal of medical genetics. Part A - 1 Jul 2003

Bamforth Fiona, Brown Lindsay, Senz Janine, Huntsman David

Abstract excerpt

Monozygotic (MZ) twins account for about one-third of all twins. Most MZ twins arise sporadically but there are familial occurrences. The causes of MZ twinning are largely speculative but involve both genetic and environmental factors. Genetic factors could include cell adhesion molecules and factors involved in growth and differentiation of the placenta and fetus. In this study, we examine the possible role of...

Topics

Cadherins
Cell Adhesion
Female
Gene Frequency
Genotype
Homozygote
Humans
Phenotype
Polymorphism, Genetic
Pregnancy
Pregnancy, Multiple
Twinning, Monozygotic
Twins, Monozygotic

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Open in PubMed

Identifiers

PMID: 12794693
DOI: 10.1002/ajmg.a.20076

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