Article
Review article: molecular basis of gastric carcinogenesis.
Alimentary pharmacology & therapeutics - 1 Jun 2003
Nardone G
Abstract excerpt
Gastric cancer is constituted by two histomorphological entities 'intestinal' and 'diffuse', however lesions with similar morphologies may differ in biological aggressiveness and response to therapy. Two distinct molecular pathways have been identified in gastric carcinogenesis: the microsatellite mutator phenotype and a phenotype associated with chromosomal and intrachromosomal instability. Mounting evidence...
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