Article
Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8.
Journal of lipid research - 1 Apr 2002
Lu Kangmo, Lee Mi-Hye, Yu Hongwei, Zhou Yuehua, Sandell Shelley A, Salen Gerald, Patel Shailendra B
Abstract excerpt
Mammalian physiological processes can distinguish between dietary cholesterol and non-cholesterol, retaining very little of the non-cholesterol in their bodies. We have recently identified two genes, ABCG5 and ABCG8, encoding sterolin-1 and -2 respectively, mutations of which cause the human disease sitosterolemia. We report here the mouse cDNAs and genomic organization of Abcg5 and Abcg8. Both genes are arranged...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
