Article
Genetic basis of sitosterolemia.
Current opinion in lipidology - 1 Apr 2001
Lee M H, Lu K, Patel S B
Abstract excerpt
The molecular mechanisms regulating the amount of dietary cholesterol retained by the body, as well as the body's ability to exclude other dietary sterols selectively, are poorly understood. An average Western diet will contain approximately 250-500 mg of dietary cholesterol and approximately 200-400 mg of non-cholesterol sterols, of which plant sterols are the major constituents. Approximately 50-60% of dietary...
Topics
- ATP-Binding Cassette Transporters
- Cholesterol
- Chromosomes, Human, Pair 2
- Female
- Homozygote
- Humans
- Lipid Metabolism, Inborn Errors
- Male
- Mutation
- Pedigree
- Sitosterols