Article
Association between dopamine receptor D3 gene BalI polymorphism and cognitive impulsiveness in alcohol-dependent men.
European psychiatry : the journal of the Association of European Psychiatrists - 1 May 2005
Limosin F, Romo L, Batel P, Adès J, Boni C, Gorwood Ph
Abstract excerpt
The gene coding for the dopamine receptor D3 (DRD3) is considered as a major candidate gene in various addictive disorders. Association studies in alcohol-dependence for this gene are nevertheless controversial. We made the hypothesis that phenotypical heterogeneity of alcohol-dependence (i.e. the DRD3 gene is a vulnerability gene in a specific subgroup of patients only) could explain these spurious findings,...
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