Article
Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting.
Genomics - 1 Jun 2003
Kayashima Tomohiko, Yamasaki Kentaro, Joh Keiichiro, Yamada Takahiro, Ohta Tohru, Yoshiura Koh-ichiro, Matsumoto Naomichi, Nakane Yoshibumi, Mukai Tsunehiro, Niikawa Norio, Kishino Tatsuya
Abstract excerpt
The mouse Atp10a gene is located at the border of an imprinted domain distal to the p-locus on mouse chromosome 7. The localization of Atp10a neighboring the maternally expressed gene Ube3a in the imprinted domain and an unusual inheritance pattern of the obesity phenotype with a p-locus deletion have suggested that Atp10a might be imprinted and associated with body fat. Recently, its human ortholog, ATP10A, was...
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