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Article

FANCF methylation contributes to chemoselectivity in ovarian cancer.

Cancer cell - 1 May 2003

Olopade Olufunmilayo I, Wei Minjie

Abstract excerpt

A new model of ovarian cancer tumor progression implicates aberrant FANCF promoter methylation that is associated with gene silencing and disruption of the Fanconi-anemia-BRCA pathway. Disruption of the pathway occurs de novo in ovarian cancers and may contribute to selective sensitivity to platinum salts.

Read the complete abstract on PubMed

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Share to BRCA1 Protein
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Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Oligonucleotide Array Sequence Analysis

Share to Ovarian Neoplasms

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Source

Identifiers

PMID: 12781358
DOI: 10.1016/s1535-6108(03)00111-9

Genes

FANCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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