Article
Origin of Hb A2' (Hb B2) [delta16(A13)Gly --> Arg (GGC --> CGC)].
Hemoglobin - 1 May 2003
Bennani Mohcine, Mombo Landry-Erik, Chaventre André, Barakat Amina, Ducrocq Rolande, Nagel Ronald L, Krishnamoorthy Rajagopal
Abstract excerpt
On a field trip to the Dogon country (le Pays Dogon) in central Mali, we detected a high frequency of the Hb A2 abnormality, reaching higher numbers among blacksmiths (up to 12.4%) living in the same villages. In this report, by direct nucleotide sequencing and employing a polymerase chain reaction-restriction fragment length polymorphism approach, we show that the Hb A2 variant observed in the Dogon population...
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