Description of two new alpha variants: Hb Canuts [alpha85(F6)Asp-->His (alpha1)] and Hb Ambroise Pare [alpha117(GH5)Phe-->Ile (alpha2)]; two new beta variants: Hb Beaujolais [beta84(EF8)Thr-->Asn] and Hb Monplaisir [beta147 (Tyr-Lys-Leu-Ala-Phe-Phe-Leu-Leu-Ser-Asn-Phe-Tyr-158-COOH)] and one new delta variant: Hb (A2)North Africa [delta59(E3)Lys-->Met].

doi:10.1080/03630260903058685

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Article

Description of two new alpha variants: Hb Canuts [alpha85(F6)Asp-->His (alpha1)] and Hb Ambroise Pare [alpha117(GH5)Phe-->Ile (alpha2)]; two new beta variants: Hb Beaujolais [beta84(EF8)Thr-->Asn] and Hb Monplaisir [beta147 (Tyr-Lys-Leu-Ala-Phe-Phe-Leu-Leu-Ser-Asn-Phe-Tyr-158-COOH)] and one new delta variant: Hb (A2)North Africa [delta59(E3)Lys-->Met].

Hemoglobin - 1 Jan 2009

Joly Philippe, Lacan Philippe, Bererd Martine, Garcia Caroline, Zanella-Cleon Isabelle, Becchi Michel, Aubry Martine, Couprie Nicole, Francina Alain

Abstract excerpt

We present here five new hemoglobin (Hb) variants which have been identified during routine Hb analysis before their genotypic characterization. Four of these result from a classical missense mutation: Hb Canuts [alpha85(F6)Asp-->His (alpha1)], Hb Ambroise Pare [alpha117(GH5)Phe-->Ile (alpha2)],...

Topics

Amino Acid Sequence
Amino Acid Substitution
Chromatography, High Pressure Liquid
DNA Mutational Analysis
Erythrocyte Indices
Frameshift Mutation
Genetic Variation
Genotype
Hemoglobinopathies
Hemoglobins, Abnormal
Humans

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Mutation, Missense

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Open in PubMed

Identifiers

PMID: 19657833
DOI: 10.1080/03630260903058685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19657833-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.