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Article

Molecular evidences of single mutational events followed by recurrent crossing-overs in the common delta-globin alleles in the Mediterranean area.

Gene - 29 Feb 2008

Lacerra Giuseppina, Musollino Gennaro, Scarano Clelia, Lagona Laura F, Caruso Daniela G, Testa Rosario, Prezioso Romeo, Di Noce Francesca, Medulla Emilia, Friscia Maria G, Mastrullo Lucia, Caldora Mercedes, Nota Lucia, Gaudiano Carlo, Magnano Carmelo, Ciaccio Calogero, Romeo Maria A, Carestia Clementina

Abstract excerpt

The human delta-globin gene (HBD) is one of the beta-like globin genes expressed in adults. In the Mediterranean countries the carriers of delta-thalassemia defects or Hb A2-variants are >1% and about 40/70 known alleles have been found in families with this ethnic origin. The scope of this study was to investigate the variability of the gene and of the chromosomal background in order to highlight the origin and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18221842
DOI: 10.1016/j.gene.2007.12.004

Genes

HBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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