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Article

Conditional expression of Mycobacterium smegmatis ftsZ, an essential cell division gene.

Microbiology (Reading, England) - 1 Jun 2003

Dziadek Jaroslaw, Rutherford Stacey A, Madiraju Murty V, Atkinson Mark A L, Rajagopalan Malini

Abstract excerpt

To understand the role of Mycobacterium smegmatis ftsZ (ftsZ(smeg)) in the cell division process, the ftsZ gene was characterized at the genetic level. This study shows that ftsZ(smeg) is an essential gene in that it can only be disrupted in a merodiploid background carrying another functional copy. Expression of ftsZ(smeg) in M. smegmatis from a constitutively active mycobacterial promoter resulted in lethality...

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Identifiers

PMID: 12777499
DOI: 10.1099/mic.0.26023-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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