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Article

60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis

26 Jun 2009

Abstract excerpt

The aim of the present study was to evaluate the expression of the heat shock protein 60 (HSP60), a mitochondrial matrix-associated protein belonging to the chaperonin family, in colorectal adenomas and cancers, comparing them to normal colonic tissues and hyperplastic polyps. We performed both immunohistochemistry and Western blot analysis for HSP60. Immunohistochemistry resulted positive in all tubular adenomas...

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PMID: 12777205
DOI: 10.4081/814

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