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Article

The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression.

Molecular and cellular biology - 1 Jun 2003

Wei Qiou, Miskimins W Keith, Miskimins Robin

Abstract excerpt

p27(Kip1) levels increase in many cells as they leave the cell cycle and begin to differentiate. The increase in p27(Kip1) levels generally precedes the expression of differentiation-specific genes. Previous studies from our laboratory showed that the overexpression of p27(Kip1) enhances myelin basic protein (MBP) promoter activity. This activation is specific to p27(Kip1). Additionally, inhibition of...

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Source

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Identifiers

PMID: 12773549
DOI: 10.1128/MCB.23.12.4035-4045.2003
PMCID: PMC156141

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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