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Article

A Role for Kit Receptor Signaling in Leydig Cell Steroidogenesis1

1 Sept 2003

Abstract excerpt

Kit and its ligand, Kitl, function in hematopoiesis, melanogenesis, and gametogenesis. In the testis, Kitl is expressed by Sertoli cells and Kit is expressed by spermatogonia and Leydig cells. Kit functions are mediated by receptor autophosphorylation and subsequent association with signaling molecules, including phosphoinositide (PI) 3-kinase. We previously characterized the reproductive consequences of blocking...

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PMID: 12773427
DOI: 10.1095/biolreprod.102.014548

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A Role for Kit Receptor Signaling in Leydig Cell Steroidogenesis1PMID 12773427Read ↗

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Kit signaling via PI3K promotes ovarian follicle maturation but is dispensable for primordial follicle activation.Semantic proximity Read ↗

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