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Article

Requirements for ICAM-1 immunogene therapy of lymphoma.

Cancer gene therapy - 1 Jun 2003

Kanwar Jagat R, Berg Randy W, Yang Yi, Kanwar Rupinder K, Ching Lai Ming, Sun Xueying, Krissansen Geoffrey W

Abstract excerpt

Intercellular cell adhesion molecule-1 (ICAM-1) is a cell-surface glycoprotein capable of eliciting bidirectional signals that activate signalling pathways in leukocytes, endothelial, and smooth muscle cells. Gene transfer of xenogeneic ICAM-1 into EL-4 lymphomas causes complete tumor rejection; however, it is unknown whether the mechanism responsible involves the "foreignness" of the ICAM-1 transgene,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12768192
DOI: 10.1038/sj.cgt.7700590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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