Article
Overexpression of glycogen synthase in mouse muscle results in less branched glycogen.
Biochemical and biophysical research communications - 13 Jun 2003
Pederson Bartholomew A, Csitkovits Anna G, Simon Renee, Schroeder Jill M, Wang Wei, Skurat Alexander V, Roach Peter J
Abstract excerpt
Glycogen, a branched polymer of glucose, serves as an energy reserve in many organisms. The degree of branching likely reflects the balance between the activities of glycogen synthase and branching enzyme. Mice overexpressing constitutively active glycogen synthase in skeletal muscle (GSL30) have elevated muscle glycogen. To test whether excess glycogen synthase activity affected glycogen branching, we examined...
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