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Article

Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease.

The Journal of biological chemistry - 9 Jan 2015

DePaoli-Roach Anna A, Contreras Christopher J, Segvich Dyann M, Heiss Christian, Ishihara Mayumi, Azadi Parastoo, Roach Peter J

Abstract excerpt

Glycogen is a branched polymer of glucose that acts as an energy reserve in many cell types. Glycogen contains trace amounts of covalent phosphate, in the range of 1 phosphate per 500-2000 glucose residues depending on the source. The function, if any, is unknown, but in at least one genetic disease, the progressive myoclonic epilepsy Lafora disease, excessive phosphorylation of glycogen has been implicated in...

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Identifiers

PMID: 25416783
DOI: 10.1074/jbc.M114.607796
PMCID: PMC4294506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease.PMID 25416783Read ↗

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