Article
Dysfunctional muscle and liver glycogen metabolism in mdx dystrophic mice.
PloS one - 1 Jan 2014
Stapleton David I, Lau Xianzhong, Flores Marcelo, Trieu Jennifer, Gehrig Stefan M, Chee Annabel, Naim Timur, Lynch Gordon S, Koopman René
Abstract excerpt
BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe, genetic muscle wasting disorder characterised by progressive muscle weakness. DMD is caused by mutations in the dystrophin (dmd) gene resulting in very low levels or a complete absence of the dystrophin protein, a key structural element of muscle fibres which is responsible for the proper transmission of force. In the absence of dystrophin, muscle fibres...
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