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Article

Allosteric regulation of glycogen synthase controls glycogen synthesis in muscle.

Cell metabolism - 3 Nov 2010

Bouskila Michale, Hunter Roger W, Ibrahim Adel F M, Delattre Lucie, Peggie Mark, van Diepen Janna A, Voshol Peter J, Jensen Jørgen, Sakamoto Kei

Abstract excerpt

Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. The relative importance of these two regulatory mechanisms in controlling GS is not establishe...

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Identifiers

PMID: 21035757
DOI: 10.1016/j.cmet.2010.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21035757-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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