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Article

Primary culture model of peroxisome proliferator-activated receptor gamma activity in prostate cancer cells.

Journal of cellular physiology - 1 Jul 2003

Xu Yue, Iyengar Sunita, Roberts Richard L, Shappell Scott B, Peehl Donna M

Abstract excerpt

BRL 49653 (rosiglitazone) is a thiazolidinedione anti-diabetic drug that activates the nuclear receptor, peroxisome proliferator-activated receptor gamma (PPARgamma). Pilot clinical trials have shown evidence of therapeutic activity of PPARgamma agonists against prostate cancer. To more effectively use PPARgamma ligands to treat this common and generally chemo-resistant type of cancer, it will be necessary to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12767049
DOI: 10.1002/jcp.10281

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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