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Identification of Differentially Expressed Genes in Keratoconus Epithelium Analyzed on Microarrays

23 May 2003

Abstract excerpt

PURPOSE: The present study was conducted to investigate differential gene expression in individual samples derived from fresh-frozen human keratoconus and normal corneal epithelium, using gene microarrays. METHODS: Total RNA was extracted (11 keratoconus and 8 normal samples), labeled, and hybridized to microarrays (GeneChip; Affymetrix, Inc., Santa Clara, CA). GeneChip data were validated by verifying the...

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PMID: 12766045
DOI: 10.1167/iovs.02-0671

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