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Article

Comparative transcriptome and network biology analyses demonstrate antiproliferative and hyperapoptotic phenotypes in human keratoconus corneas.

Investigative ophthalmology & visual science - 3 Aug 2011

Macé Matthias, Galiacy Stéphane D, Erraud Angélique, Mejía José Enrique, Etchevers Heather, Allouche Michèle, Desjardins Laurence, Calvas Patrick, Malecaze François

Abstract excerpt

PURPOSE: To decipher the biological pathways involved in keratoconus pathophysiology by determining the patterns of differential gene expression between keratoconus and control corneas. METHODS: RNA was extracted from surgically removed corneas of 10 keratoconus patients and from normal corneas of 10 control patients who had undergone enucleation of an eye for ocular melanoma. Several hundred thousand RNA...

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PMID: 21676910
DOI: 10.1167/iovs.10-70981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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