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Article

Omics in Keratoconus: From Molecular to Clinical Practice

3 Apr 2025

Abstract excerpt

Keratoconus (KC) is a progressive ocular disorder marked by structural and functional alterations of the cornea, leading to significant visual impairment. Recent studies indicate that these corneal changes are linked to molecular and cellular mechanisms that disrupt and degrade the extracellular matrix. This degradation is influenced by proteinases that contribute to a loss of homeostasis and an imbalance in the...

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PMID: 40217908
DOI: 10.3390/jcm14072459

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