Article
An algorithm for identification of regulatory signals in unaligned DNA sequences, its testing and parallel implementation.
In silico biology - 1 Jan 2003
Danilova Ludmila V, Lyubetsky Vassily A, Gelfand Mikhail S
Abstract excerpt
We describe an algorithm (IRSA) for identification of common regulatory signals in samples of unaligned DNA sequences. The algorithm was tested on randomly generated sequences of fixed length with implanted signal of length 15 with 4 mutations, and on natural upstream regions of bacterial genes regulated by PurR, ArgR and CRP. Then it was applied to upstream regions of orthologous genes from Escherichia coli and...
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