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Article

Tight-adherence genes of Actinobacillus actinomycetemcomitans are required for virulence in a rat model.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2003

Schreiner Helen C, Sinatra Kathy, Kaplan Jeffrey B, Furgang David, Kachlany Scott C, Planet Paul J, Perez Brenda A, Figurski David H, Fine Daniel H

Abstract excerpt

Actinobacillus actinomycetemcomitans is a Gram-negative coccobacillus that has been associated with localized aggressive periodontitis and infections of the heart, brain, and urinary tract. Wild-type clinical isolates have the remarkable ability to adhere tenaciously and nonspecifically to solid surfaces such as glass, plastic, and hydroxyapatite. Adherence by A. actinomycetemcomitans is mediated by the...

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Identifiers

PMID: 12756291
DOI: 10.1073/pnas.1237223100
PMCID: PMC165869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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