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Article

Phenotypic variation in Actinobacillus actinomycetemcomitans during laboratory growth: implications for virulence.

Microbiology (Reading, England) - 1 Jun 1999

Fine Daniel H, Furgang David, Schreiner Helen C, Goncharoff Paul, Charlesworth Jon, Ghazwan Ghazi, Fitzgerald-Bocarsly Patricia, Figurski David H

Abstract excerpt

This study examined alteration of specific virulence traits associated with phenotypic changes seen when a low-passage disease-associated and well maintained parent strain of Actinobacillus actinomycetemcomitans was compared to a laboratory-grown spontaneous variant/mutant. Clinical isolates of A. actinomycetemcomitans recovered from periodontitis patients typically grow as rough, adherent colonies on primary...

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PMID: 10411260
DOI: 10.1099/13500872-145-6-1335

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