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Article

A regulatory mutant of Hansenula polymorpha exhibiting methanol utilization metabolism and peroxisome proliferation in glucose.

Journal of bacteriology - 1 Jun 1998

Parpinello G, Berardi E, Strabbioli R

Abstract excerpt

Mutant LGM-128 of Hansenula polymorpha harbors the recessive mutation glr2-1 which confers a complex pleiotropic phenotype, the major feature of which is the metabolically unnecessary induction of methanol utilization metabolism (C1 metabolism) during growth on glucose, whether or not methanol is in the medium. Therefore, in this mutant, peroxisomes are formed and proliferate upon cultivation in...

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Identifiers

PMID: 9603888
DOI: 10.1128/JB.180.11.2958-2967.1998
PMCID: PMC107265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A regulatory mutant of Hansenula polymorpha exhibiting methanol utilization metabolism and peroxisome proliferation in glucose.PMID 9603888Read ↗

Hansenula polymorpha: an attractive model organism for molecular studies of peroxisome biogenesis and function.Semantic proximity Read ↗

Methanol metabolism in a peroxisome-deficient mutant of Hansenula polymorpha: a physiological study.Semantic proximity Read ↗

Characterization of peroxisome-deficient mutants of Hansenula polymorpha.Semantic proximity Read ↗

Selective inactivation of alcohol oxidase in two peroxisome-deficient mutants of the yeast Hansenula polymorpha.Semantic proximity Read ↗

Glucose-induced production of recombinant proteins in Hansenula polymorpha mutants deficient in catabolite repression.Semantic proximity Read ↗

Restoration of peroxisome formation in two conditional peroxisome-deficient mutants of Hansenula polymorpha during growth of cells on specific organic nitrogen sources.Semantic proximity Read ↗

Isolation of mutants of Hansenula polymorpha defective in the assembly of octameric alcohol oxidase.Semantic proximity Read ↗

Peroxisome biogenesis in Hansenula polymorpha: different mutations in genes, essential for peroxisome biogenesis, cause different peroxisomal mutant phenotypes.Semantic proximity Read ↗

The Hansenula polymorpha per6 mutant is affected in two adjacent genes which encode dihydroxyacetone kinase and a novel protein, Pak1p, involved in peroxisome integrity.Semantic proximity Read ↗

Nitrogen metabolite repression in Hansenda polymorpha: the nmrl-l mutation.Semantic proximity Read ↗

Peroxisome biogenesis in the yeast Hansenula polymorpha is controlled by a complex set of interacting gene products.Semantic proximity Read ↗

Peroxisomes in the methylotrophic yeast Hansenula polymorpha do not necessarily derive from pre-existing organelles.Semantic proximity Read ↗

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