Article
Interferon-gamma receptor-1 gene polymorphism in tuberculosis patients from Croatia.
Scandinavian journal of immunology - 1 May 2003
Fraser D A, Bulat-Kardum L, Knezevic J, Babarovic P, Matakovic-Mileusnic N, Dellacasagrande J, Matanic D, Pavelic J, Beg-Zec Z, Dembic Z
Abstract excerpt
Recent studies have indicated that the interleukin-12/interferon-gamma (IFN-gamma) axis is important in mycobacterial infection susceptibility. Using an intronic (CA)n polymorphic microsatellite marker within the IFN-gamma receptor-1 (IFNGR1) gene, we have compared the allelic frequencies of this marker in hospitalized tuberculosis patients (n = 120) with that of controls (n = 87) from Rijeka, Croatia. We...
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