Article

Enhancement of BMP-2-Induced Osteogenic Differentiation of MC3T3-E1 Cells by Dexamethasone through the Smad Signaling Pathway

2024-05-06

Abstract excerpt

<title>Abstract</title> <p>Tissue-engineered bone is a promising approach for repairing defects in the jawbone caused by tumors, infections, trauma, and congenital malformations, with BMP-2 playing a key role. Clinically, to achieve favorable therapeutic outcomes, the doses of BMP-2 used far exceed the physiological levels found in natural bone, leading to various side effects.To investigate the effectiveness and...

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Literature Corpus work: c3d583bc-2ba8-5b0a-8867-826ccbdc4f1a
DOI: 10.21203/rs.3.rs-4303918/v1

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