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Article

Genetic analysis of a synaptic calcium channel in Drosophila: intragenic modifiers of a temperature-sensitive paralytic mutant of cacophony.

Genetics - 1 May 2003

Brooks I M, Felling R, Kawasaki F, Ordway R W

Abstract excerpt

Our previous genetic analysis of synaptic mechanisms in Drosophila identified a temperature-sensitive paralytic mutant of the voltage-gated calcium channel alpha1 subunit gene, cacophony (cac). Electrophysiological studies in this mutant, designated cac(TS2), indicated cac encodes a primary calcium channel alpha1 subunit functioning in neurotransmitter release. To further examine the functions and interactions of...

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Identifiers

PMID: 12750329
DOI: 10.1093/genetics/164.1.163
PMCID: PMC1462532

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