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Article

Estrogens in Testis Biology

1 Dec 2005

Abstract excerpt

Levels of estrogen within the male reproductive tract are higher than in the general circulation and the aromatase enzyme is expressed in the adult testis. Estrogens such as estradiol (E2) modify cell function by binding to high-affinity estrogen receptors (ER). Two subtypes (ERalpha and ERbeta) have been identified. Studies in animals have shown that over- or underexposure to estrogens can have an impact on...

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PMID: 16467258
DOI: 10.1196/annals.1336.008

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