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Article

Human Ejaculated Spermatozoa Contain Active P450 Aromatase

1 Jul 2002

Abstract excerpt

The generation of cytochrome P450 aromatase (P450arom) and estrogen receptor (ER) knockout mice has raised new interest in the physiological role of estrogens in male reproduction. Testicular expression of P450arom, the enzyme that converts androgens into estrogens, has been shown in both somatic and germ cell types in several species, whereas in humans, testicular expression is confined to the somatic cells. The...

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PMID: 12107254
DOI: 10.1210/jcem.87.7.8633

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