Article
Interaction of soft condensed materials with living cells: phenotype/transcriptome correlations for the hydrophobic effect.
Proceedings of the National Academy of Sciences of the United States of America - 27 May 2003
Allen Lorcan T, Fox Edward J P, Blute Irena, Kelly Zoe D, Rochev Yuri, Keenan Alan K, Dawson Kenneth A, Gallagher William M
Abstract excerpt
The assessment of biomaterial compatibility relies heavily on the analysis of macroscopic cellular responses to material interaction. However, new technologies have become available that permit a more profound understanding of the molecular basis of cell-biomaterial interaction. Here, both conventional phenotypic and contemporary transcriptomic (DNA microarray-based) analysis techniques were combined to examine...
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