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Article

PTS1-independent targeting of isocitrate lyase to peroxisomes requires the PTS1 receptor Pex5p.

Molecular membrane biology - 1 Jan 2000

Parkes John A, Langer Sigrid, Hartig Andreas, Baker Alison

Abstract excerpt

The targeting of castor bean isocitrate lyase to peroxisomes was studied by expression in the heterologous host Saccharomyces cerevisae from which the endogenous ICL1 gene had been removed by gene disruption. Peroxisomal import of ICL was dependent upon the PTS1 receptor Pex5p and was lost by deletion of the last three amino acids, Ala-Arg-Met. However, removal of an additional 16 amino acids restored the ability...

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Identifiers

PMID: 12745927
DOI: 10.1080/0968768031000047859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PTS1-independent targeting of isocitrate lyase to peroxisomes requires the PTS1 receptor Pex5p.PMID 12745927Read ↗

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