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Article

Structure and regulation of the isocitrate lyase gene ICL1 from the yeast Saccharomyces cerevisiae.

Current genetics - 1 Jan 2000

Schöler A, Schüller H J

Abstract excerpt

The ICL1 gene encoding the isocitrate lyase from Saccharomyces cerevisiae was cloned and sequenced. A reading frame of 557 amino acids showing significant similarity to isocitrate lyases from seven other species could be identified. Construction of icl1 null mutants led to growth defects on C2 carbon sources while utilization of sugars or C3 substrates remained unaffected. Using an ICL1-lacZ fusion integrated at...

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PMID: 8319292
DOI: 10.1007/BF00312621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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