Article
Analyses of polymorphism for UGT1*1 exon 1 promoter in neonates with pathologic and prolonged jaundice.
Biology of the neonate - 1 Jan 2003
Ulgenalp A, Duman N, Schaefer F V, Whetsell L, Bora E, Gülcan H, Kumral A, Oren H, Giray O, Erçal D, Ozkan H
Abstract excerpt
In this study, we investigated whether a TATA box polymorphism in the promoter of the UGT1*1 exon I, the most common detected DNA polymorphism in Gilbert's syndrome, is a contributory factor in unexplained pathologic or prolonged jaundice. 38 neonates who had unexplained pathologic jaundice, 37 neonates who had unexplained prolonged jaundice, and 35 healthy, nonjaundiced neonates were enrolled in the study....
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