Article
Absolute values of dendritic cell subsets in bone marrow, cord blood, and peripheral blood enumerated by a novel method.
Stem cells (Dayton, Ohio) - 1 Jan 2003
Szabolcs Paul, Park Kyung-Duk, Reese Melissa, Marti Luciana, Broadwater Gloria, Kurtzberg Joanne
Abstract excerpt
Dendritic cells (DCs) are pivotal in inducing immunity or alternatively downregulating immune reactivity. In humans, the opposing phenotypic subsets of CD11c(+)/CD123(-) "myeloid" DCs and CD123(+)/CD11c(-) "lymphoid" DCs have been proposed to orchestrate these immune responses. In this study we determined the absolute numbers of both subsets in three resting hematopoietic tissues by employing a novel flow...
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