Article
Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa.
Molecular psychiatry - 1 Apr 2003
Bergen A W, van den Bree M B M, Yeager M, Welch R, Ganjei J K, Haque K, Bacanu S, Berrettini W H, Grice D E, Goldman D, Bulik C M, Klump K, Fichter M, Halmi K, Kaplan A, Strober M, Treasure J, Woodside B, Kaye W H
Abstract excerpt
Serotonergic and opioidergic neurotransmitter system alterations have been observed in people with eating disorders; the genes for the serotonin 1D receptor (HTR1D) and the opioid delta receptor (OPRD1) are found on chr1p36.3-34.3, a region identified by our group in a linkage analysis of anorexia nervosa (AN). These candidate genes were evaluated for sequence variation and for linkage and association of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.