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Article

Regulation of hepatitis C virus replication via threonine phosphorylation of the NS5A protein.

The Journal of general virology - 1 Jan 2018

Goonawardane Niluka, Ross-Thriepland Douglas, Harris Mark

Abstract excerpt

The hepatitis C virus non-structural 5A (NS5A) protein is highly phosphorylated and plays roles in both virus genome replication and assembly of infectious virus particles. NS5A comprises three domains separated by low complexity sequences (LCS). Mass spectrometry analysis of NS5A revealed the existence of a singly phosphorylated tryptic peptide corresponding to the end of LCS I and the beginning of domain II...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29139348
DOI: 10.1099/jgv.0.000975
PMCID: PMC5882090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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