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Article

Genetic variation of circulating leptin is involved in genetic variation of hand bone size and geometry.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jul 2003

Livshits Gregory, Pantsulaia I, Pantsulaia Ia, Trofimov Svetlana, Kobyliansky Eugene

Abstract excerpt

Leptin is secreted primarily by the adipocytes and plays an important role in the regulation of food intake and energy expenditure. In addition to its adipostatic function, it has been demonstrated that leptin directly enhances stromal cell differentiation to osteoblasts, and since such precursor cells are potential targets for leptin, the latter could possibly mediate the relationship between obesity and bone...

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PMID: 12739104
DOI: 10.1007/s00198-003-1383-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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